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Membrane steroid receptor : ウィキペディア英語版 | Membrane steroid receptor Membrane steroid receptors (mSRs), also called extranuclear steroid receptors, are a class of receptors that bind and are activated by endogenous steroids and mediate rapid, non-genomic signaling via modulation of intracellular signaling cascades. They are another means besides classical nuclear steroid hormone receptors by which steroids mediate their biological effects.〔〔〔〔 Known groups of mSRs include: * Membrane sex steroid receptors * * Membrane estrogen receptors (mERs) – e.g., GPER * * Membrane progesterone receptors (mPRs) * * Membrane androgen receptors (mARs) * Membrane corticosteroid receptors * * Membrane glucocorticoid receptors (mGRs) * * Membrane mineralocorticoid receptors (mMRs) Ligand-gated ion channels such as the GABAA receptor and the NMDA receptor bind and are modulated by neurosteroids such as dehydroepiandrosterone (DHEA), allopregnanolone, and 3α-androstanediol. Vomeronasal receptors bind and are activated by pheromones such as androstenone and androstenol. ==References==
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